University: We Make Lives Better

Barshop Institute for Longevity and Aging Studies

Roberto J. Fajardo, M.D.


Roberto J. Fajardo, M.D.

Assistant Professor/Research
Department of Medicine - Orthopaedics
University of Texas Health Science Center at San Antonio
Office: 210-567-6176


My primary research investigates the impact of type 2 diabetes on fracture prevalence and risk in Latinos and other populations. In recent work, we showed that vertebral fracture prevalence is dramatically altered in diabetic Latinos compared to non-diabetic Latinos. My work now includes two main thrusts: population studies of diabetic vertebral fragility with emphasis on identifying clinical markers predictive of fracture/fracture risk. In addition, we are beginning to investigate the cell and tissue level changes in diabetic bone tissue collected from spine surgeries. It is of particular importance to determine causes, predictive markers, and appropriate therapeutic interventions. Latinos are the fastest growing ethnic demographic group in the United States. At the same time, Latinos have twice the risk of developing type 2 diabetes compared to non-Latino Caucasians. The confluence of population growth rates and the risks of type 2 diabetes and associated fracture risks suggest that some emphasis be placed on this issue.

Finally, I am the on-site director for the annual Healing the Children medical mission to Neiva, Colombia. This mission provides oromaxillofacial (cleft palate, cleft lip), plastics (burn sequelae), and orthopaedics surgeries (hip dysplasia and club foot) to approximately 185-200 children over a five day period. Our team typically consists of 40 volunteers from 5+ countries. This work is an amazing labor of love by everyone. If you are interested in getting involved, contact me.

Selected Publications

J.E. Schmitz; J.D. Teepe; Y. Hu; C.E. Smith; R.J. Fajardo; Y.-H.P. Chun Estimating mineral changes in enamel formation by ashing/BSE and microCT Journal of Dental Research. 2014;93(3):256-262.

Ramaswamy Sharma; Danielle Callaway; Difernando Vanegas; Michelle Bendele; Marisa Lopez-Cruzan; Diane Horn; Teja Guda; Roberto Fajardo; Sherry Abboud-Werner; Brian Herman Caspase-2 maintains bone homeostasis by inducing apoptosis of oxidatively-damaged osteoclasts PLoS ONE. 2014;9(4).

Roberto J. Fajardo; Lamya Karim; Virginia I. Calley; Mary L. Bouxsein A review of rodent models of type 2 diabetic skeletal fragility Journal of Bone and Mineral Research. 2014;29(5):1025-1040.


BarshopINSTITUTElogo _Converted_
The Sam and Ann Barshop Institute for Longevity and Aging Studies

15355 Lambda Drive
San Antonio, Texas  78245
P: 210-562-6140 F: 210-562-6150

Copyright © 2018
UT Health San Antonio

The University of Texas Health Science Center
Accessibility | Public/Personal Information | Site Information | Web Privacy

Links from web sites affiliated with The University of Texas Health Science Center's web site ( to other web sites do not constitute or imply university endorsement of those sites, their content, or products and services associated with those sites.

Site Developed by Toolbox Studios, Inc.